Detalhe da pesquisa
1.
Immunohistochemical detection of PAX-FOXO1 fusion proteins in alveolar rhabdomyosarcoma using breakpoint specific monoclonal antibodies.
Mod Pathol
; 34(4): 748-757, 2021 04.
Artigo
em Inglês
| MEDLINE | ID: mdl-33299109
2.
Clinicopathologic and molecular analysis of embryonal rhabdomyosarcoma of the genitourinary tract: evidence for a distinct DICER1-associated subgroup.
Mod Pathol
; 34(8): 1558-1569, 2021 08.
Artigo
em Inglês
| MEDLINE | ID: mdl-33846547
3.
PAX3-FOXO1: Zooming in on an "undruggable" target.
Semin Cancer Biol
; 50: 115-123, 2018 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-29146205
4.
Unpeaceful roles of mutant PAX proteins in cancer.
Semin Cell Dev Biol
; 44: 126-34, 2015 Aug.
Artigo
em Inglês
| MEDLINE | ID: mdl-26391565
5.
FGFR4 signaling couples to Bim and not Bmf to discriminate subsets of alveolar rhabdomyosarcoma cells.
Int J Cancer
; 135(7): 1543-52, 2014 Oct 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-24550147
6.
Preferred analysis methods for single genomic regions in RNA sequencing revealed by processing the shape of coverage.
Nucleic Acids Res
; 40(9): e63, 2012 May.
Artigo
em Inglês
| MEDLINE | ID: mdl-22210855
7.
Functional Classification of Fusion Proteins in Sarcoma.
Cancers (Basel)
; 16(7)2024 Mar 29.
Artigo
em Inglês
| MEDLINE | ID: mdl-38611033
8.
The Chromatin Remodeler CHD4 Sustains Ewing Sarcoma Cell Survival by Controlling Global Chromatin Architecture.
Cancer Res
; 84(2): 241-257, 2024 01 16.
Artigo
em Inglês
| MEDLINE | ID: mdl-37963210
9.
Evaluation of the role of AXL in fusion-positive pediatric rhabdomyosarcoma identifies the small-molecule inhibitor bemcentinib (BGB324) as potent chemosensitizer.
Mol Cancer Ther
; 2024 Mar 13.
Artigo
em Inglês
| MEDLINE | ID: mdl-38471796
10.
Elimusertib has Antitumor Activity in Preclinical Patient-Derived Pediatric Solid Tumor Models.
Mol Cancer Ther
; 23(4): 507-519, 2024 Apr 02.
Artigo
em Inglês
| MEDLINE | ID: mdl-38159110
11.
Genomic and Epigenetic Changes Drive Aberrant Skeletal Muscle Differentiation in Rhabdomyosarcoma.
Cancers (Basel)
; 15(10)2023 May 18.
Artigo
em Inglês
| MEDLINE | ID: mdl-37345159
12.
Single-cell profiling of alveolar rhabdomyosarcoma reveals RAS pathway inhibitors as cell-fate hijackers with therapeutic relevance.
Sci Adv
; 9(6): eade9238, 2023 02 10.
Artigo
em Inglês
| MEDLINE | ID: mdl-36753540
13.
PAX3-FOXO1 uses its activation domain to recruit CBP/P300 and shape RNA Pol2 cluster distribution.
Nat Commun
; 14(1): 8361, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38102136
14.
MYOD-SKP2 axis boosts tumorigenesis in fusion negative rhabdomyosarcoma by preventing differentiation through p57Kip2 targeting.
Nat Commun
; 14(1): 8373, 2023 Dec 15.
Artigo
em Inglês
| MEDLINE | ID: mdl-38102140
15.
Small-molecule screen identifies modulators of EWS/FLI1 target gene expression and cell survival in Ewing's sarcoma.
Int J Cancer
; 131(9): 2153-64, 2012 Nov 01.
Artigo
em Inglês
| MEDLINE | ID: mdl-22323082
16.
Inhibition of HDACs reduces Ewing sarcoma tumor growth through EWS-FLI1 protein destabilization.
Neoplasia
; 27: 100784, 2022 05.
Artigo
em Inglês
| MEDLINE | ID: mdl-35366465
17.
CRISPR activation screen identifies TGFß-associated PEG10 as a crucial tumor suppressor in Ewing sarcoma.
Sci Rep
; 12(1): 10671, 2022 06 23.
Artigo
em Inglês
| MEDLINE | ID: mdl-35739280
18.
Fenretinide Acts as Potent Radiosensitizer for Treatment of Rhabdomyosarcoma Cells.
Front Oncol
; 11: 664462, 2021.
Artigo
em Inglês
| MEDLINE | ID: mdl-34211841
19.
A combinatorial drug screen in PDX-derived primary rhabdomyosarcoma cells identifies the NOXA - BCL-XL/MCL-1 balance as target for re-sensitization to first-line therapy in recurrent tumors.
Neoplasia
; 23(9): 929-938, 2021 09.
Artigo
em Inglês
| MEDLINE | ID: mdl-34329950
20.
Paracrine Placental Growth Factor Signaling in Response to Ionizing Radiation Is p53-Dependent and Contributes to Radioresistance.
Mol Cancer Res
; 19(6): 1051-1062, 2021 06.
Artigo
em Inglês
| MEDLINE | ID: mdl-33619227